Symptoms and treatment of hemophilia – As an orphan disease due to its rare condition, hemophilia is a pathology that affects around 500,000 people worldwide, which states their quality of life to a great extent. This article will learn a little more about it, its symptoms, how it, and the most appropriate treatment currently exists.
Hemophilia: A Strange Genetic Evil
Hemophilia is a hereditary disease that directly affects blood coagulation and causes, among those who suffer from it, bleeding that lasts much longer than usual. Produces, in most cases, a considerable increase in bleeding risk due to the lack of proteins necessary to stop bleeding.
The first references to this disease. Date to the 2nd century AD, when some boys bled when circumcised. Later, in the 19th century, the first studies were carried out and determined its genetic disease status.
The disease causes continuous bleeding only if the patient undergoes surgery or suffers trauma in its mildest form. In moderate cases, the lack of coagulation produces certain types of fractures, while in more severe cases, bleeding can occur spontaneously.
Any bleeding poses a greater risk for those with this disease because Their blood does clot properly.
In most cases, men who acquire this condition inherited from their mothers suffer the disease. In them, the blood lacks a coagulation factor necessary to stop bleeding.
This disease into type A hemophilia. Those affected have low levels of factor 8 and type B hemophilia, in which patients do not produce enough factor 9. The most common condition is type A, accounting for about 85% of cases worldwide.
Symptoms and Treatment of Hemophilia – In both types, the disease manifests itself in the same way: extensive bruising, the sensation of a particular kind of pain, stiffness, swelling and bleeding within the muscles and joints. In more severe cases, spontaneous bleeding can occur inside the body for no particular reason.
One of the most shared manifestations of the disease is when long-lasting bleeding occurs after a cut, a surgical intervention or an extraction procedure. Hemophilia can also cause joint problems.
Bleeding can be both external and internal. These occur in the muscles and joints in most cases, with the knees, ankles and elbows, and the upper arm and calf muscles being most affected.
Likewise, the hemorrhages generated in a hemophilia patient can lead to arthritis or some other type of disease related to the joints. Especially those of the lower limbs. The affected person may present serious difficulties when walking in the long run. In risky cases where the patient does not receive adequate care, this disease can lead to death.
What causes Hemophilia?
Hemophilia by contagion. This disease by a change in one of the genes located on the X chromosome, which is why it mainly affects men, while women tend to carry the alteration.
To understand it better, we must clarify that women have two X chromosomes, one inherited from their father and their mother. In contrast, men have an X chromosome inherited from their father and a Y chromosome inherited from their mother.
Now, the X chromosome has many genes not present on the Y chromosome. Men have only one copy of the genetic factor on the X chromosome, while women have two copies. Therefore, men can have the disease if they inherit the affected X chromosome.
Thus, the sons of a father with hemophilia will be healthy while his daughters will inherit the deficient copy of the X chromosome but not develop the disease. In the case of the sons of carrier women, they have a 50% chance of suffering from hemophilia. And the daughters have a 50% chance of being carriers.
Current Treatment of Hemophilia
Even though there mending treatment accessible to treat hemophilia, the current way replaces the missing coagulating component to permit the blood to cluster appropriately. Accomplished with the infusion prescriptions uniquely ready reason, managed all of the time specialist hematologists.
In the most complicated cases, factor replacement therapy should at least three times a week. This treatment, called prophylaxis, can be carried out by the affected patient himself. Managing to stop the bleeding and, in some cases, prevent bleeding.
Those affected by hemophilia should avoid engaging in risky activities, such as extreme or contact sports. Some disciplines, such as tennis or swimming, can be supervised.
These changes in the lifestyle of those who have the disease allow them to lead an everyday life. These people, in addition. Must carry a plate with which they identified as hemophiliac patients. Something significant in cases in which they may suffer an accident.
Knowledge of the disease. How your body works and what activities you can or cannot do, are essential tasks that every patient with hemophilia must perform. Thus, with the necessary care, you will be able to carry out a routine, raising your quality of life.